Cargando…
On the discovery of a potential survivin inhibitor combining computational tools and cytotoxicity studies
Survivin protein is a metalloprotein member of the inhibitors of apoptosis proteins family, involved in the regulation of programmed cell death. Due to the recent development of antitumor therapies having survivin as molecular target, several strategies to interfere with the expression or function o...
Autores principales: | Quispe, Patricia A., Lavecchia, Martin J., León, Ignacio E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699424/ https://www.ncbi.nlm.nih.gov/pubmed/31440594 http://dx.doi.org/10.1016/j.heliyon.2019.e02238 |
Ejemplares similares
-
Discovery of Survivin Inhibitors Part 1: Screening the Harbor Branch Pure Compound Library
por: Guzmán, Esther A., et al.
Publicado: (2021) -
Novel Survivin Peptides Screened With Computer Algorithm Induce Cytotoxic T Lymphocytes With Higher Cytotoxic Efficiency to Cancer Cells
por: Chen, Qiuqiang, et al.
Publicado: (2020) -
Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells
por: Niu, Huiyan, et al.
Publicado: (2011) -
Identification of Inhibitors against Metastasis Protein “Survivin:” In silico Discovery Using Virtual Screening and Molecular Docking Studies
por: Mishra, Swechha, et al.
Publicado: (2017) -
Discovery of Novel 3-Cyanopyridines as Survivin Modulators and Apoptosis Inducers
por: Sabour, Rehab, et al.
Publicado: (2020)