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Hydrogen sulfide donor GYY4137 suppresses proliferation of human colorectal cancer Caco-2 cells by inducing both cell cycle arrest and cell death

Conflicting data regarding the ability of hydrogen sulfide (H(2)S), which reaches high levels in the large intestine owing to biosynthesis in the intestinal cells and intestinal bacteria, to promote or inhibit colorectal cancer cell proliferation have been reported recently. In the present study, th...

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Detalles Bibliográficos
Autores principales: Sakuma, Satoru, Minamino, Saaya, Takase, Maya, Ishiyama, Yoshitaka, Hosokura, Hiroyuki, Kohda, Tetsuya, Ikeda, Yukino, Fujimoto, Yohko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699460/
https://www.ncbi.nlm.nih.gov/pubmed/31440595
http://dx.doi.org/10.1016/j.heliyon.2019.e02244