Alda-1 Prevents Pulmonary Epithelial Barrier Dysfunction following Severe Hemorrhagic Shock through Clearance of Reactive Aldehydes

Severe hemorrhagic shock and resuscitation (HS/R) can lead to lung injury, resulting in respiratory insufficiency. We investigated whether treatment with Alda-1, an ALDH2 activator, decreased lung injury induced by severe HS/R in a rat model. Male Sprague-Dawley rats were randomized into three group...

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Detalles Bibliográficos
Autores principales: Hua, Tianfeng, Yang, Min, Zhou, Yangyang, Chen, Limin, Wu, Huimei, Liu, Rongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699483/
https://www.ncbi.nlm.nih.gov/pubmed/31467875
http://dx.doi.org/10.1155/2019/2476252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699483/
https://www.ncbi.nlm.nih.gov/pubmed/31467875
http://dx.doi.org/10.1155/2019/2476252

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