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APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan

Age and apolipoprotein E (APOE) e4 genotype are two of the strongest known risk factors for sporadic Alzheimer's disease (AD). Neuroimaging has shown hemodynamic response changes with age, in asymptomatic carriers of the APOE e4 allele, and in AD. In this study, we aimed to characterize and dif...

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Detalles Bibliográficos
Autores principales: Rasmussen, Peter M., Aamand, Rasmus, Weitzberg, Eddie, Christiansen, Michael, Østergaard, Leif, Lund, Torben E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699560/
https://www.ncbi.nlm.nih.gov/pubmed/31408838
http://dx.doi.org/10.1016/j.nicl.2019.101955