Cargando…

Overexpression of protein phosphatase 5 in the mouse heart: Reduced contractility but increased stress tolerance – Two sides of the same coin?

The pathophysiological mechanisms of sepsis-induced cardiac dysfunction are largely unknown. The Toll-like receptor 4 (TLR4) is expressed in cardiac myocytes and is involved in bacterial endotoxin-mediated inflammatory disorders. TLR4 signaling leads to activation of the nuclear factor kappa B follo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gergs, Ulrich, Jahn, Tina, Werner, Franziska, Köhler, Carolin, Köpp, Friedrich, Großmann, Claudia, Neumann, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699691/
https://www.ncbi.nlm.nih.gov/pubmed/31425567
http://dx.doi.org/10.1371/journal.pone.0221289