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Overexpression of protein phosphatase 5 in the mouse heart: Reduced contractility but increased stress tolerance – Two sides of the same coin?
The pathophysiological mechanisms of sepsis-induced cardiac dysfunction are largely unknown. The Toll-like receptor 4 (TLR4) is expressed in cardiac myocytes and is involved in bacterial endotoxin-mediated inflammatory disorders. TLR4 signaling leads to activation of the nuclear factor kappa B follo...
Autores principales: | Gergs, Ulrich, Jahn, Tina, Werner, Franziska, Köhler, Carolin, Köpp, Friedrich, Großmann, Claudia, Neumann, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699691/ https://www.ncbi.nlm.nih.gov/pubmed/31425567 http://dx.doi.org/10.1371/journal.pone.0221289 |
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