Systemic expression of Alu RNA in patients with geographic atrophy secondary to age-related macular degeneration

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is characterized by irreversible loss of macular retinal tissue and retinal pigment epithelium (RPE) cells. Several studies have revealed that accumulation of Alu RNA in RPE cell causes RPE cell degeneration in AMD. In the p...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshida, Hiroyuki, Matsushita, Tokiyoshi, Kimura, Erika, Fujita, Yukie, Keany, Robert, Ikeda, Toshihiro, Toshimori, Masanao, Imanaka, Takahiro, Nakamura, Masatsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699695/
https://www.ncbi.nlm.nih.gov/pubmed/31425537
http://dx.doi.org/10.1371/journal.pone.0220887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699695/
https://www.ncbi.nlm.nih.gov/pubmed/31425537
http://dx.doi.org/10.1371/journal.pone.0220887

Ejemplares similares