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Blood flow guides sequential support of neutrophil arrest and diapedesis by PILR-β1 and PILR-α

Arrest of rapidly flowing neutrophils in venules relies on capturing through selectins and chemokine-induced integrin activation. Despite a long-established concept, we show here that gene inactivation of activating paired immunoglobulin-like receptor (PILR)-β1 nearly halved the efficiency of neutro...

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Detalles Bibliográficos
Autores principales: Li, Yu-Tung, Goswami, Debashree, Follmer, Melissa, Artz, Annette, Pacheco-Blanco, Mariana, Vestweber, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699825/
https://www.ncbi.nlm.nih.gov/pubmed/31385804
http://dx.doi.org/10.7554/eLife.47642