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Tick saliva protein Evasin-3 modulates chemotaxis by disrupting CXCL8 interactions with glycosaminoglycans and CXCR2

Chemokines are a group of chemotaxis proteins that regulate cell trafficking and play important roles in immune responses and inflammation. Ticks are blood-sucking parasites that secrete numerous immune-modulatory agents in their saliva to evade host immune responses. Evasin-3 is a small salivary pr...

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Detalles Bibliográficos
Autores principales: Denisov, Stepan S., Ippel, Johannes H., Heinzmann, Alexandra C. A., Koenen, Rory R., Ortega-Gomez, Almudena, Soehnlein, Oliver, Hackeng, Tilman M., Dijkgraaf, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699855/
https://www.ncbi.nlm.nih.gov/pubmed/31235521
http://dx.doi.org/10.1074/jbc.RA119.008902