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Characterization of behavioral phenotypes in the BTBR T(+) Itpr3(tf)/J mouse model of autism spectrum disorder under social housing conditions using the multiple animal positioning system

The BTBR T(+) Itpr3(tf)/J (BTBR) mouse strain is a widely used model of autism spectrum disorder (ASD). The BTBR mice display behavior consistent with the three diagnostic categories of ASD. However, the behavioral phenotypes of the BTBR mice in a long-term group housing setting are largely unknown...

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Detalles Bibliográficos
Autores principales: Endo, Nozomi, Makinodan, Manabu, Somayama, Nami, Komori, Takashi, Kishimoto, Toshifumi, Nishi, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699967/
https://www.ncbi.nlm.nih.gov/pubmed/30905912
http://dx.doi.org/10.1538/expanim.18-0177