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Melatonin prevents chronic intermittent hypoxia-induced injury by inducing sirtuin 1-mediated autophagy in steatotic liver of mice

BACKGROUND: Hepatic steatosis that occasionally results in nonalcoholic steatohepatitis (NASH) is related to obstructive sleep apnea (OSA). Many studies have shown that autophagy exerts protective effects on liver damage caused by various diseases and melatonin exhibits hepatoprotective properties....

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Detalles Bibliográficos
Autores principales: Ren, Jie, Jin, Meng, You, Zhen-xi, Luo, Miao, Han, Yin, Li, Guang-cai, Liu, Hui-guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700047/
https://www.ncbi.nlm.nih.gov/pubmed/30411173
http://dx.doi.org/10.1007/s11325-018-1741-4