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A TLR–CXCL1 pathway in DRG neurons induces neutrophil accumulation in the DRG and mechanical allodynia in EAE mice

Multiple sclerosis (MS) is a potentially disabling disease of the central nervous system. Approximately half of the patients with MS experience severe pain; however, currently available therapeutics provide only insufficient relief. The mechanisms underlying the generation of neuropathic pain in pat...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Harada, Yuka, Hayashi, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700073/
https://www.ncbi.nlm.nih.gov/pubmed/31427756
http://dx.doi.org/10.1038/s41598-019-48558-7