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Tissue-specific progesterone receptor-chromatin binding and the regulation of progesterone-dependent gene expression
Progesterone receptor (PGR) co-ordinately regulates ovulation, fertilisation and embryo implantation through tissue-specific actions, but the mechanisms for divergent PGR action are poorly understood. Here we characterised PGR activity in mouse granulosa cells using combined ChIP-seq for PGR and H3K...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700090/ https://www.ncbi.nlm.nih.gov/pubmed/31427604 http://dx.doi.org/10.1038/s41598-019-48333-8 |