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Comprehensive characterization of RAS mutations in colon and rectal cancers in old and young patients

Colorectal cancer (CRC) is increasingly appreciated as a heterogeneous disease, with factors such as microsatellite instability (MSI), cancer subsite within the colon versus rectum, and age of diagnosis associated with specific disease course and therapeutic response. Activating oncogenic mutations...

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Detalles Bibliográficos
Autores principales: Serebriiskii, Ilya G., Connelly, Caitlin, Frampton, Garrett, Newberg, Justin, Cooke, Matthew, Miller, Vince, Ali, Siraj, Ross, Jeffrey S., Handorf, Elizabeth, Arora, Sanjeevani, Lieu, Christopher, Golemis, Erica A., Meyer, Joshua E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700103/
https://www.ncbi.nlm.nih.gov/pubmed/31427573
http://dx.doi.org/10.1038/s41467-019-11530-0