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The anti-tumor function of the IKK inhibitor PS1145 and high levels of p65 and KLF4 are associated with the drug resistance in nasopharyngeal carcinoma cells

We and others have previously shown that the canonical nuclear factor kappa-B (NF-κB) pathway is essential to nasopharyngeal carcinoma (NPC) tumor development and angiogenesis, suggesting that the NF-κB pathway, including its upstream modulators and downstream effectors, are potential therapeutic ta...

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Detalles Bibliográficos
Autores principales: Lung, Hong Lok, Kan, Rebecca, Chau, Wai Yin, Man, On Ying, Mak, Nai Ki, Fong, Chun Hung, Shuen, Wai Ho, Tsao, Sai Wah, Lung, Maria Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700134/
https://www.ncbi.nlm.nih.gov/pubmed/31427673
http://dx.doi.org/10.1038/s41598-019-48590-7