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The anti-tumor function of the IKK inhibitor PS1145 and high levels of p65 and KLF4 are associated with the drug resistance in nasopharyngeal carcinoma cells
We and others have previously shown that the canonical nuclear factor kappa-B (NF-κB) pathway is essential to nasopharyngeal carcinoma (NPC) tumor development and angiogenesis, suggesting that the NF-κB pathway, including its upstream modulators and downstream effectors, are potential therapeutic ta...
Autores principales: | Lung, Hong Lok, Kan, Rebecca, Chau, Wai Yin, Man, On Ying, Mak, Nai Ki, Fong, Chun Hung, Shuen, Wai Ho, Tsao, Sai Wah, Lung, Maria Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700134/ https://www.ncbi.nlm.nih.gov/pubmed/31427673 http://dx.doi.org/10.1038/s41598-019-48590-7 |
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