Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy

We report changes in the genomic landscape in the development of head and neck squamous cell carcinomas HNSCC from potentially premalignant lesions (PPOLS) to malignancy and lymph node metastases. Likely pathological mutations predominantly involved a relatively small set of genes reported previousl...

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Detalles Bibliográficos
Autores principales: Veeramachaneni, Ratna, Walker, Thomas, Revil, Timothée, Weck, Antoine De, Badescu, Dunarel, O’Sullivan, James, Higgins, Catherine, Elliott, Louise, Liloglou, Triantafillos, Risk, Janet M., Shaw, Richard, Hampson, Lynne, Hampson, Ian, Dearden, Simon, Woodwards, Robert, Prime, Stephen, Hunter, Keith, Parkinson, Eric Kenneth, Ragoussis, Jiannis, Thakker, Nalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700135/
https://www.ncbi.nlm.nih.gov/pubmed/31427592
http://dx.doi.org/10.1038/s41598-019-48229-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700135/
https://www.ncbi.nlm.nih.gov/pubmed/31427592
http://dx.doi.org/10.1038/s41598-019-48229-7

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