The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis

Renal fibrosis is accompanied by the progression of chronic kidney disease. Despite a number of past and ongoing studies, our understanding of the underlying mechanisms remains elusive. Here we explored the progression of renal fibrosis using a mouse model of unilateral ureter obstruction. We found...

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Detalles Bibliográficos
Autores principales: Koyano, Takayuki, Namba, Masumi, Kobayashi, Tomoe, Nakakuni, Kyomi, Nakano, Daisuke, Fukushima, Masaki, Nishiyama, Akira, Matsuyama, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700145/
https://www.ncbi.nlm.nih.gov/pubmed/31427681
http://dx.doi.org/10.1038/s41598-019-48557-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700145/
https://www.ncbi.nlm.nih.gov/pubmed/31427681
http://dx.doi.org/10.1038/s41598-019-48557-8

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