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The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis
Renal fibrosis is accompanied by the progression of chronic kidney disease. Despite a number of past and ongoing studies, our understanding of the underlying mechanisms remains elusive. Here we explored the progression of renal fibrosis using a mouse model of unilateral ureter obstruction. We found...
Autores principales: | Koyano, Takayuki, Namba, Masumi, Kobayashi, Tomoe, Nakakuni, Kyomi, Nakano, Daisuke, Fukushima, Masaki, Nishiyama, Akira, Matsuyama, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700145/ https://www.ncbi.nlm.nih.gov/pubmed/31427681 http://dx.doi.org/10.1038/s41598-019-48557-8 |
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