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IP(3) receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

Contact sites of endoplasmic reticulum (ER) and mitochondria locally convey calcium signals between the IP(3) receptors (IP3R) and the mitochondrial calcium uniporter, and are central to cell survival. It remains unclear whether IP3Rs also have a structural role in contact formation and whether the...

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Detalles Bibliográficos
Autores principales: Bartok, Adam, Weaver, David, Golenár, Tünde, Nichtova, Zuzana, Katona, Máté, Bánsághi, Száva, Alzayady, Kamil J., Thomas, V. Kaye, Ando, Hideaki, Mikoshiba, Katsuhiko, Joseph, Suresh K., Yule, David I., Csordás, György, Hajnóczky, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700175/
https://www.ncbi.nlm.nih.gov/pubmed/31427578
http://dx.doi.org/10.1038/s41467-019-11646-3