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IP(3) receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer
Contact sites of endoplasmic reticulum (ER) and mitochondria locally convey calcium signals between the IP(3) receptors (IP3R) and the mitochondrial calcium uniporter, and are central to cell survival. It remains unclear whether IP3Rs also have a structural role in contact formation and whether the...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700175/ https://www.ncbi.nlm.nih.gov/pubmed/31427578 http://dx.doi.org/10.1038/s41467-019-11646-3 |