Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP(+)-induced neuronal death

Parkinson’s disease (PD) is a chronic neurodegenerative disease with no cure. Calbindin, a Ca(2+)-buffering protein, has been suggested to have a neuroprotective effect in the brain tissues of PD patients and in experimental models of PD. However, the underlying mechanisms remain elusive. Here, we r...

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Detalles Bibliográficos
Autores principales: Jung, Shinae, Chung, Yuhyun, Lee, Yunsoo, Lee, Yangsin, Cho, Jin Won, Shin, Eun-Joo, Kim, Hyoung-Chun, Oh, Young J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700189/
https://www.ncbi.nlm.nih.gov/pubmed/31452956
http://dx.doi.org/10.1038/s41420-019-0210-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700189/
https://www.ncbi.nlm.nih.gov/pubmed/31452956
http://dx.doi.org/10.1038/s41420-019-0210-6

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