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Buffering of cytosolic calcium plays a neuroprotective role by preserving the autophagy-lysosome pathway during MPP(+)-induced neuronal death
Parkinson’s disease (PD) is a chronic neurodegenerative disease with no cure. Calbindin, a Ca(2+)-buffering protein, has been suggested to have a neuroprotective effect in the brain tissues of PD patients and in experimental models of PD. However, the underlying mechanisms remain elusive. Here, we r...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700189/ https://www.ncbi.nlm.nih.gov/pubmed/31452956 http://dx.doi.org/10.1038/s41420-019-0210-6 |