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In-silico Design of DNA Oligonucleotides: Challenges and Approaches
DNA oligonucleotides are essential components of a high number of technologies in molecular biology. The key event of each oligonucleotide-based assay is the specific binding between oligonucleotides and their target DNA. However, single-stranded DNA molecules also tend to bind to unintended targets...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Research Network of Computational and Structural Biotechnology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700205/ https://www.ncbi.nlm.nih.gov/pubmed/31452858 http://dx.doi.org/10.1016/j.csbj.2019.07.008 |