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Sphingomyelin Breakdown in T Cells: Role of Membrane Compartmentalization in T Cell Signaling and Interference by a Pathogen

Sphingolipids are major components of cellular membranes, and at steady-state level, their metabolic fluxes are tightly controlled. On challenge by external signals, they undergo rapid turnover, which substantially affects the biophysical properties of membrane lipid and protein compartments and, co...

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Detalles Bibliográficos
Autores principales: Avota, Elita, de Lira, Maria Nathalia, Schneider-Schaulies, Sibylle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700246/
https://www.ncbi.nlm.nih.gov/pubmed/31457008
http://dx.doi.org/10.3389/fcell.2019.00152