An Efficient Approach to Aromatic Aminomethylation Using Dichloromethane as Methylene Source

Ultrasound-promoted N-aminomethylation of indoles can be achieved in basic medium using sodium hydride and dichloromethane (DCM) as C1 donor source. This innovative amino methylation protocol results in good to excellent yields of multifunctional indole derivatives. The procedure is also applicable...

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Detalles Bibliográficos
Autores principales: Ostacolo, Carmine, Di Sarno, Veronica, Musella, Simona, Ciaglia, Tania, Vestuto, Vincenzo, Pepe, Giacomo, Merciai, Fabrizio, Campiglia, Pietro, Gomez Monterrey, Isabel M., Bertamino, Alessia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700257/
https://www.ncbi.nlm.nih.gov/pubmed/31457005
http://dx.doi.org/10.3389/fchem.2019.00568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700257/
https://www.ncbi.nlm.nih.gov/pubmed/31457005
http://dx.doi.org/10.3389/fchem.2019.00568

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