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EFhd2 Affects Tau Liquid–Liquid Phase Separation

The transition of tau proteins from its soluble physiological conformation to the pathological aggregate forms found in Alzheimer’s disease and related dementias, is poorly understood. Therefore, understanding the process that modulates the formation of toxic tau oligomers and their conversion to pu...

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Detalles Bibliográficos
Autores principales: Vega, Irving E., Umstead, Andrew, Kanaan, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700279/
https://www.ncbi.nlm.nih.gov/pubmed/31456657
http://dx.doi.org/10.3389/fnins.2019.00845