Cargando…
EFhd2 Affects Tau Liquid–Liquid Phase Separation
The transition of tau proteins from its soluble physiological conformation to the pathological aggregate forms found in Alzheimer’s disease and related dementias, is poorly understood. Therefore, understanding the process that modulates the formation of toxic tau oligomers and their conversion to pu...
Autores principales: | Vega, Irving E., Umstead, Andrew, Kanaan, Nicholas M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700279/ https://www.ncbi.nlm.nih.gov/pubmed/31456657 http://dx.doi.org/10.3389/fnins.2019.00845 |
Ejemplares similares
-
Tau’s Three-Repeat Domain and EFhd2 Co-incubation Leads to Increased Thioflavin Signal
por: Vega, Irving E., et al.
Publicado: (2018) -
Liquid-liquid phase separation induces pathogenic tau conformations in vitro
por: Kanaan, Nicholas M., et al.
Publicado: (2020) -
Tau protein liquid–liquid phase separation can initiate tau aggregation
por: Wegmann, Susanne, et al.
Publicado: (2018) -
EFhd2, a Protein Linked to Alzheimer's Disease and Other Neurological Disorders
por: Vega, Irving E.
Publicado: (2016) -
Interplay between tau and α‐synuclein liquid–liquid phase separation
por: Siegert, Anna, et al.
Publicado: (2021)