CAG Repeat Not Polyglutamine Length Determines Timing of Huntington’s Disease Onset

Variable, glutamine-encoding, CAA interruptions indicate that a property of the uninterrupted HTT CAG repeat sequence, distinct from the length of huntingtin’s polyglutamine segment, dictates the rate at which Huntington’s disease (HD) develops. The timing of onset shows no significant association w...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700281/
https://www.ncbi.nlm.nih.gov/pubmed/31398342
http://dx.doi.org/10.1016/j.cell.2019.06.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700281/
https://www.ncbi.nlm.nih.gov/pubmed/31398342
http://dx.doi.org/10.1016/j.cell.2019.06.036

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