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Conditional Deletion of the V-ATPase a2-Subunit Disrupts Intrathymic T Cell Development
Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from cell surface receptors to the nucleus, shaping a distinct transcriptional program t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700305/ https://www.ncbi.nlm.nih.gov/pubmed/31456807 http://dx.doi.org/10.3389/fimmu.2019.01911 |