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Conditional Deletion of the V-ATPase a2-Subunit Disrupts Intrathymic T Cell Development

Proper orchestration of T lymphocyte development is critical, as T cells underlie nearly all responses of the adaptive immune system. Developing thymocytes differentiate in response to environmental cues carried from cell surface receptors to the nucleus, shaping a distinct transcriptional program t...

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Detalles Bibliográficos
Autores principales: Peterson, Theodore V., Jaiswal, Mukesh K., Beaman, Kenneth D., Reynolds, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700305/
https://www.ncbi.nlm.nih.gov/pubmed/31456807
http://dx.doi.org/10.3389/fimmu.2019.01911