Contactin 1 modulates pegylated arginase resistance in small cell lung cancer through induction of epithelial–mesenchymal transition

Drug resistance is a major hurdle in the treatment of small cell lung cancer (SCLC). Previously we demonstrated the potential anticancer effect of pegylated arginase BCT-100 in SCLC cell lines and xenograft models. To facilitate future clinical application of BCT-100 in SCLC treatment, we elucidated...

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Detalles Bibliográficos
Autores principales: Xu, Shi, Lam, Sze-Kwan, Cheng, Paul Ning-Man, Ho, James Chung-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700313/
https://www.ncbi.nlm.nih.gov/pubmed/31427725
http://dx.doi.org/10.1038/s41598-019-48476-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700313/
https://www.ncbi.nlm.nih.gov/pubmed/31427725
http://dx.doi.org/10.1038/s41598-019-48476-8

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