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Direct-Acting Antiviral Treatment of HCV Infection Does Not Resolve the Dysfunction of Circulating CD8(+) T-Cells in Advanced Liver Disease
Chronic hepatitis C virus (HCV) infection disrupts immune functions, including that of cytotoxic CD8(+) T-cells which are important mediators of immune response. While HCV cure aims to eliminate long term sequelae of infection, whether direct-acting antiviral (DAA) treatment results in immune recons...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700371/ https://www.ncbi.nlm.nih.gov/pubmed/31456810 http://dx.doi.org/10.3389/fimmu.2019.01926 |