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Direct-Acting Antiviral Treatment of HCV Infection Does Not Resolve the Dysfunction of Circulating CD8(+) T-Cells in Advanced Liver Disease

Chronic hepatitis C virus (HCV) infection disrupts immune functions, including that of cytotoxic CD8(+) T-cells which are important mediators of immune response. While HCV cure aims to eliminate long term sequelae of infection, whether direct-acting antiviral (DAA) treatment results in immune recons...

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Detalles Bibliográficos
Autores principales:	Vranjkovic, Agatha, Deonarine, Felicia, Kaka, Shaima, Angel, Jonathan B., Cooper, Curtis L., Crawley, Angela M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700371/ https://www.ncbi.nlm.nih.gov/pubmed/31456810 http://dx.doi.org/10.3389/fimmu.2019.01926

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