Linking Molecular Pathways and Large-Scale Computational Modeling to Assess Candidate Disease Mechanisms and Pharmacodynamics in Alzheimer's Disease

Introduction: While the prevalence of neurodegenerative diseases associated with dementia such as Alzheimer's disease (AD) increases, our knowledge on the underlying mechanisms, outcome predictors, or therapeutic targets is limited. In this work, we demonstrate how computational multi-scale bra...

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Detalles Bibliográficos
Autores principales: Stefanovski, Leon, Triebkorn, Paul, Spiegler, Andreas, Diaz-Cortes, Margarita-Arimatea, Solodkin, Ana, Jirsa, Viktor, McIntosh, Anthony Randal, Ritter, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700386/
https://www.ncbi.nlm.nih.gov/pubmed/31456676
http://dx.doi.org/10.3389/fncom.2019.00054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700386/
https://www.ncbi.nlm.nih.gov/pubmed/31456676
http://dx.doi.org/10.3389/fncom.2019.00054

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