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Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells

Cancer cells generally harbor hundreds of alterations in the cancer genomes and act as crucial factors in the development and progression of cancer. Gene alterations in the cancer genome form genetic interactions, which affect the response of patients to drugs. We developed an algorithm that mines c...

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Detalles Bibliográficos
Autores principales: Han, Yue, Wang, Chengyu, Dong, Qi, Chen, Tingting, Yang, Fan, Liu, Yaoyao, Chen, Bo, Zhao, Zhangxiang, Qi, Lishuang, Zhao, Wenyuan, Liang, Haihai, Guo, Zheng, Gu, Yunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700431/
https://www.ncbi.nlm.nih.gov/pubmed/31400611
http://dx.doi.org/10.1016/j.omtn.2019.07.003