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Genetic Interaction-Based Biomarkers Identification for Drug Resistance and Sensitivity in Cancer Cells
Cancer cells generally harbor hundreds of alterations in the cancer genomes and act as crucial factors in the development and progression of cancer. Gene alterations in the cancer genome form genetic interactions, which affect the response of patients to drugs. We developed an algorithm that mines c...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700431/ https://www.ncbi.nlm.nih.gov/pubmed/31400611 http://dx.doi.org/10.1016/j.omtn.2019.07.003 |