p85α Inactivates MMP-2 and Suppresses Bladder Cancer Invasion by Inhibiting MMP-14 Transcription and TIMP-2 Degradation

Recent studies show p85α up-regulates epidermal growth factor (EGF) receptor, thereby promoting malignant cell transformation and migration in normal mouse embryonic fibroblasts (MEFs). However, the potential role of p85α in human bladder cancer (BC) remains unknown. Here, we show that p85α is down-...

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Detalles Bibliográficos
Autores principales: Wang, Jingjing, Zhang, Ning, Peng, Minggang, Hua, Xiaohui, Huang, Chao, Tian, Zhongxian, Xie, Qipeng, Zhu, Junlan, Li, Jingxia, Huang, Haishan, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700442/
https://www.ncbi.nlm.nih.gov/pubmed/31401412
http://dx.doi.org/10.1016/j.neo.2019.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700442/
https://www.ncbi.nlm.nih.gov/pubmed/31401412
http://dx.doi.org/10.1016/j.neo.2019.07.007

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