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Long-Term Safety, Immunologic Response, and Imaging Outcomes following Neural Stem Cell Transplantation for Pelizaeus-Merzbacher Disease

Four boys with Pelizaeus-Merzbacher disease, an X-linked leukodystrophy, underwent transplantation with human allogeneic central nervous system stem cells (HuCNS-SC). Subsequently, all subjects were followed for an additional 4 years in this separate follow-up study to evaluate safety, neurologic fu...

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Detalles Bibliográficos
Autores principales: Gupta, Nalin, Henry, Roland G., Kang, Sang-Mo, Strober, Jonathan, Lim, Daniel A., Ryan, Tamara, Perry, Rachel, Farrell, Jody, Ulman, Mary, Rajalingam, Raja, Gage, Allyson, Huhn, Stephen L., Barkovich, A. James, Rowitch, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700500/
https://www.ncbi.nlm.nih.gov/pubmed/31378671
http://dx.doi.org/10.1016/j.stemcr.2019.07.002