A Minor Subpopulation of Mycobacteria Inherently Produces High Levels of Reactive Oxygen Species That Generate Antibiotic Resisters at High Frequency From Itself and Enhance Resister Generation From Its Major Kin Subpopulation

Antibiotic-exposed bacteria produce elevated levels of reactive oxygen species (ROS), to which either they succumb or get mutated genome-wide to generate antibiotic resisters. We recently showed that mycobacterial cultures contained two subpopulations, short-sized cells (SCs; ∼10%) and normal/long-s...

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Detalles Bibliográficos
Autores principales: Nair, Rashmi Ravindran, Sharan, Deepti, Ajitkumar, Parthasarathi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700507/
https://www.ncbi.nlm.nih.gov/pubmed/31456773
http://dx.doi.org/10.3389/fmicb.2019.01842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700507/
https://www.ncbi.nlm.nih.gov/pubmed/31456773
http://dx.doi.org/10.3389/fmicb.2019.01842

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