Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients

Generation of functional β cells from pluripotent sources would accelerate diagnostic and therapeutic applications for diabetes research and therapy. However, it has been challenging to generate competent β cells with dynamic insulin-secretory capacity to glucose and incretin stimulations. We introd...

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Detalles Bibliográficos
Autores principales: Zhu, Yaxi, Tonne, Jason M., Liu, Qian, Schreiber, Claire A., Zhou, Zhiguang, Rakshit, Kuntol, Matveyenko, Aleksey V., Terzic, Andre, Wigle, Dennis, Kudva, Yogish C., Ikeda, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700523/
https://www.ncbi.nlm.nih.gov/pubmed/31378674
http://dx.doi.org/10.1016/j.stemcr.2019.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700523/
https://www.ncbi.nlm.nih.gov/pubmed/31378674
http://dx.doi.org/10.1016/j.stemcr.2019.07.006

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