Decreased Disposition of Anticancer Drugs Predominantly Eliminated via the Liver in Patients with Renal Failure

BACKGROUND: Evidence has revealed that renal impairment can affect the systemic exposure of drugs which are predominantly eliminated via the liver. The modulation of drug-metabolizing enzymes and transporters expressed in the liver and/or small intestine by diverse entities, including uremic toxins,...

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Detalles Bibliográficos
Autores principales: Fujita, Ken-ichi, Matsumoto, Natsumi, Ishida, Hiroo, Kubota, Yutaro, Iwai, Shinichi, Shibanuma, Motoko, Kato, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700602/
https://www.ncbi.nlm.nih.gov/pubmed/30947665
http://dx.doi.org/10.2174/1389200220666190402143125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700602/
https://www.ncbi.nlm.nih.gov/pubmed/30947665
http://dx.doi.org/10.2174/1389200220666190402143125

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