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Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture

Aiming at clinical translation, robust directed differentiation of human pluripotent stem cells (hPSCs), preferentially in chemically defined conditions, is a key requirement. Here, feasibility of suspension culture based hPSC-cardiomyocyte (hPSC-CM) production in low-cost, xeno-free media compatibl...

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Detalles Bibliográficos
Autores principales: Halloin, Caroline, Schwanke, Kristin, Löbel, Wiebke, Franke, Annika, Szepes, Monika, Biswanath, Santoshi, Wunderlich, Stephanie, Merkert, Sylvia, Weber, Natalie, Osten, Felix, de la Roche, Jeanne, Polten, Felix, Wollert, Kai, Kraft, Theresia, Fischer, Martin, Martin, Ulrich, Gruh, Ina, Kempf, Henning, Zweigerdt, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700605/
https://www.ncbi.nlm.nih.gov/pubmed/31353227
http://dx.doi.org/10.1016/j.stemcr.2019.06.004