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Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
Aiming at clinical translation, robust directed differentiation of human pluripotent stem cells (hPSCs), preferentially in chemically defined conditions, is a key requirement. Here, feasibility of suspension culture based hPSC-cardiomyocyte (hPSC-CM) production in low-cost, xeno-free media compatibl...
Autores principales: | Halloin, Caroline, Schwanke, Kristin, Löbel, Wiebke, Franke, Annika, Szepes, Monika, Biswanath, Santoshi, Wunderlich, Stephanie, Merkert, Sylvia, Weber, Natalie, Osten, Felix, de la Roche, Jeanne, Polten, Felix, Wollert, Kai, Kraft, Theresia, Fischer, Martin, Martin, Ulrich, Gruh, Ina, Kempf, Henning, Zweigerdt, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700605/ https://www.ncbi.nlm.nih.gov/pubmed/31353227 http://dx.doi.org/10.1016/j.stemcr.2019.06.004 |
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