Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture

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Aiming at clinical translation, robust directed differentiation of human pluripotent stem cells (hPSCs), preferentially in chemically defined conditions, is a key requirement. Here, feasibility of suspension culture based hPSC-cardiomyocyte (hPSC-CM) production in low-cost, xeno-free media compatibl...

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Detalles Bibliográficos
Autores principales: Halloin, Caroline, Schwanke, Kristin, Löbel, Wiebke, Franke, Annika, Szepes, Monika, Biswanath, Santoshi, Wunderlich, Stephanie, Merkert, Sylvia, Weber, Natalie, Osten, Felix, de la Roche, Jeanne, Polten, Felix, Wollert, Kai, Kraft, Theresia, Fischer, Martin, Martin, Ulrich, Gruh, Ina, Kempf, Henning, Zweigerdt, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700605/
https://www.ncbi.nlm.nih.gov/pubmed/31353227
http://dx.doi.org/10.1016/j.stemcr.2019.06.004
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