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Downregulation of mTOR Signaling Increases Stem Cell Population Telomere Length during Starvation of Immortal Planarians

Reduction of caloric intake delays and prevents age-associated diseases and extends the life span in many organisms. It may be that these benefits are due to positive effects of caloric restriction on stem cell function. We use the planarian model Schmidtea mediterranea, an immortal animal that adap...

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Detalles Bibliográficos
Autores principales: Iglesias, Marta, Felix, Daniel A., Gutiérrez-Gutiérrez, Óscar, De Miguel-Bonet, Maria del Mar, Sahu, Sounak, Fernández-Varas, Beatriz, Perona, Rosario, Aboobaker, A. Aziz, Flores, Ignacio, González-Estévez, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700675/
https://www.ncbi.nlm.nih.gov/pubmed/31353226
http://dx.doi.org/10.1016/j.stemcr.2019.06.005