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Downregulation of mTOR Signaling Increases Stem Cell Population Telomere Length during Starvation of Immortal Planarians
Reduction of caloric intake delays and prevents age-associated diseases and extends the life span in many organisms. It may be that these benefits are due to positive effects of caloric restriction on stem cell function. We use the planarian model Schmidtea mediterranea, an immortal animal that adap...
Autores principales: | Iglesias, Marta, Felix, Daniel A., Gutiérrez-Gutiérrez, Óscar, De Miguel-Bonet, Maria del Mar, Sahu, Sounak, Fernández-Varas, Beatriz, Perona, Rosario, Aboobaker, A. Aziz, Flores, Ignacio, González-Estévez, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700675/ https://www.ncbi.nlm.nih.gov/pubmed/31353226 http://dx.doi.org/10.1016/j.stemcr.2019.06.005 |
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