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Bone morphogenetic protein-7 represses hepatic stellate cell activation and liver fibrosis via regulation of TGF-β/Smad signaling pathway

BACKGROUND: Liver fibrosis is a refractory disease whose persistence can eventually induce cirrhosis or even liver cancer. Early liver fibrosis is reversible by intervention. As a member of the transforming growth factor-beta (TGF-β) superfamily, bone morphogenetic protein 7 (BMP7) has anti-liver fi...

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Detalles Bibliográficos
Autores principales: Zou, Gao-Liang, Zuo, Shi, Lu, Shuang, Hu, Rui-Han, Lu, Yin-Ying, Yang, Jing, Deng, Kai-Sheng, Wu, Ye-Ting, Mu, Mao, Zhu, Juan-Juan, Zeng, Jing-Zhang, Zhang, Bao-Fang, Wu, Xian, Zhao, Xue-Ke, Li, Hai-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700693/
https://www.ncbi.nlm.nih.gov/pubmed/31435175
http://dx.doi.org/10.3748/wjg.v25.i30.4222