Cargando…

Bone morphogenetic protein-7 represses hepatic stellate cell activation and liver fibrosis via regulation of TGF-β/Smad signaling pathway

BACKGROUND: Liver fibrosis is a refractory disease whose persistence can eventually induce cirrhosis or even liver cancer. Early liver fibrosis is reversible by intervention. As a member of the transforming growth factor-beta (TGF-β) superfamily, bone morphogenetic protein 7 (BMP7) has anti-liver fi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Gao-Liang, Zuo, Shi, Lu, Shuang, Hu, Rui-Han, Lu, Yin-Ying, Yang, Jing, Deng, Kai-Sheng, Wu, Ye-Ting, Mu, Mao, Zhu, Juan-Juan, Zeng, Jing-Zhang, Zhang, Bao-Fang, Wu, Xian, Zhao, Xue-Ke, Li, Hai-Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2019
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700693/ https://www.ncbi.nlm.nih.gov/pubmed/31435175 http://dx.doi.org/10.3748/wjg.v25.i30.4222

Ejemplares similares

Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway
por: Mu, Mao, et al.
Publicado: (2018)

Ferulic acid attenuates liver fibrosis and hepatic stellate cell activation via inhibition of TGF-β/Smad signaling pathway [Corrigendum]
por: Mu, Mao, et al.
Publicado: (2019)

Notch signaling mediated by TGF-β/Smad pathway in concanavalin A-induced liver fibrosis in rats
por: Wang, Yi, et al.
Publicado: (2017)

Naringenin prevents experimental liver fibrosis by blocking TGFβ-Smad3 and JNK-Smad3 pathways
por: Hernández-Aquino, Erika, et al.
Publicado: (2017)

Effect of Exogenous Fetuin-A on TGF-β/Smad Signaling in Hepatic Stellate Cells
por: Zhou, Yulai, et al.
Publicado: (2016)

Smad7-overexpressing rat BMSCs inhibit the fibrosis of hepatic stellate cells by regulating the TGF-β1/Smad signaling pathway
por: Wu, Shi-Pin, et al.
Publicado: (2017)

Fasudil prevents liver fibrosis via activating natural killer cells and suppressing hepatic stellate cells
por: Han, Qiu-Ju, et al.
Publicado: (2021)

Calcitriol attenuates liver fibrosis through hepatitis C virus nonstructural protein 3-transactivated protein 1-mediated TGF β1/Smad3 and NF-κB signaling pathways
por: Shi, Liu, et al.
Publicado: (2023)

Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice
por: Huang, Ping, et al.
Publicado: (2022)

Glutathione prevents high glucose-induced pancreatic fibrosis by suppressing pancreatic stellate cell activation via the ROS/TGFβ/SMAD pathway
por: Zhang, Jitai, et al.
Publicado: (2022)

Fluorofenidone affects hepatic stellate cell activation in hepatic fibrosis by targeting the TGF-β1/Smad and MAPK signaling pathways
por: Peng, Yu, et al.
Publicado: (2019)

Role of Tenascin-X in regulating TGF-β/Smad signaling pathway in pathogenesis of slow transit constipation
por: Zhang, Yi-Chao, et al.
Publicado: (2020)

Immunohistochemical Expression of TGF-Β1, SMAD4, SMAD7, TGFβRII and CD68-Positive TAM Densities in Papillary Thyroid Cancer
por: Ivanova, Koni, et al.
Publicado: (2018)

Angiotensin-converting enzyme 2 improves liver fibrosis in mice by regulating autophagy of hepatic stellate cells
por: Wu, Ying, et al.
Publicado: (2023)

Lysyl hydroxylase 3 increases collagen deposition and promotes pulmonary fibrosis by activating TGFβ1/Smad3 and Wnt/β-catenin pathways
por: Shao, Songjun, et al.
Publicado: (2019)

PU.1 inhibition attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin‐II by reducing TGF‐β1/Smads pathway activation
por: Hu, Juan, et al.
Publicado: (2021)

Emodin Retarded Renal Fibrosis Through Regulating HGF and TGFβ–Smad Signaling Pathway
por: Yang, Fan, et al.
Publicado: (2020)

Casticin attenuates liver fibrosis and hepatic stellate cell activation by blocking TGF-β/Smad signaling pathway
por: Zhou, Ling, et al.
Publicado: (2017)

Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling
por: Huang, Qian, et al.
Publicado: (2022)

Caffeic acid phenethyl ester up-regulates antioxidant levels in hepatic stellate cell line T6 via an Nrf2-mediated mitogen activated protein kinases pathway
por: Yang, Ning, et al.
Publicado: (2017)

Bone Morphogenetic Protein-7 Antagonizes Myocardial Fibrosis Induced by Atrial Fibrillation by Restraining Transforming Growth Factor-β (TGF-β)/Smads Signaling
por: Chen, Xinjun, et al.
Publicado: (2016)

MicroRNA-194 inactivates hepatic stellate cells and alleviates liver fibrosis by inhibiting AKT2
por: Wu, Jun-Cheng, et al.
Publicado: (2019)

Coexpression of Smad7 and UPA attenuates carbon tetrachloride-induced rat liver fibrosis
por: Wang, Baocan, et al.
Publicado: (2012)

EZH2‐mediated repression of Dkk1 promotes hepatic stellate cell activation and hepatic fibrosis
por: Yang, Yang, et al.
Publicado: (2017)

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways
por: Wu, Liwei, et al.
Publicado: (2017)

Trimetazidine inhibits liver fibrosis and hepatic stellate cell proliferation and blocks transforming growth factor-β (TGFβ)/Smad signaling in vitro and in vivo
por: Ding, Wenwen, et al.
Publicado: (2022)

Aspirin inhibits endometrial fibrosis by suppressing the TGF-β1-Smad2/Smad3 pathway in intrauterine adhesions
por: Zhang, Zihui, et al.
Publicado: (2020)

Inhibitory effects of oxymatrine on hepatic stellate cells activation through TGF-β/miR-195/Smad signaling pathway
por: Song, Li-Ying, et al.
Publicado: (2019)

Rebalancing TGF‐β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis
por: Yang, Yang, et al.
Publicado: (2021)

Expression of angiotensinogen during hepatic fibrogenesis and its effect on hepatic stellate cells
por: Lu, Ping, et al.
Publicado: (2011)

Acupuncture attenuates renal interstitial fibrosis via the TGF-β/Smad pathway
por: Zuo, Zheng, et al.
Publicado: (2019)

Fluorofenidone alleviates liver fibrosis by inhibiting hepatic stellate cell autophagy via the TGF-β1/Smad pathway: implications for liver cancer
por: Peng, Xiongqun, et al.
Publicado: (2023)

Transforming growth factor beta-1 upregulates glucose transporter 1 and glycolysis through canonical and noncanonical pathways in hepatic stellate cells
por: Zhou, Ming-Yu, et al.
Publicado: (2021)

Upregulation of GLT25D1 in Hepatic Stellate Cells Promotes Liver Fibrosis via the TGF-β1/SMAD3 Pathway In Vivo and In vitro
por: Wang, Shiwei, et al.
Publicado: (2023)

Caveolin-1 Scaffolding Domain Peptides Alleviate Liver Fibrosis by Inhibiting TGF-β1/Smad Signaling in Mice
por: Lu, Jing, et al.
Publicado: (2018)

ENMD-1068 inhibits liver fibrosis through attenuation of TGF-β1/Smad2/3 signaling in mice
por: Sun, Quan, et al.
Publicado: (2017)

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Discovery of Matrinic Thiadiazole Derivatives as a Novel Family of Anti-Liver Fibrosis Agents via Repression of the TGFβ/Smad Pathway
por: Niu, Tianyu, et al.
Publicado: (2018)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2
por: Tee, Jie Kai, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6it6m1pgie8qlk9jcoqpjqo1g1