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Oral Delivery of miRNA With Lipidic Aminoglycoside Derivatives in the Breastfed Rat

CONTEXT: Specific targeting of endogenous miRNAs which are involved in epigenetics, may help understanding homeostasis with therapeutic benefits. We use new biologically inspired vehicles consisting of lipoaminoglycosides to deliver in vivo mir-320-3p, a known human breast milk exosomal miRNA, or it...

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Detalles Bibliográficos
Autores principales: Beuzelin, Diane, Pitard, Bruno, Kaeffer, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700720/
https://www.ncbi.nlm.nih.gov/pubmed/31456698
http://dx.doi.org/10.3389/fphys.2019.01037