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Silencing of miR-182 is associated with modulation of tumorigenesis through apoptosis induction in an experimental model of colorectal cancer

BACKGROUND: miR-182-5p (miR-182) is an oncogenic microRNA (miRNA) found in different tumor types and one of the most up-regulated miRNA in colorectal cancer (CRC). Although this microRNA is expressed in the early steps of tumor development, its role in driving tumorigenesis is unclear. METHODS: The...

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Detalles Bibliográficos
Autores principales: Perilli, Lisa, Tessarollo, Sofia, Albertoni, Laura, Curtarello, Matteo, Pastò, Anna, Brunetti, Efrem, Fassan, Matteo, Rugge, Massimo, Indraccolo, Stefano, Amadori, Alberto, Bortoluzzi, Stefania, Zanovello, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700772/
https://www.ncbi.nlm.nih.gov/pubmed/31429725
http://dx.doi.org/10.1186/s12885-019-5982-9