A model of pulldown alignments from SssI-treated DNA improves DNA methylation prediction

BACKGROUND: Protein pulldown using Methyl-CpG binding domain (MBD) proteins followed by high-throughput sequencing is a common method to determine DNA methylation. Algorithms have been developed to estimate absolute methylation level from read coverage generated by affinity enrichment-based techniqu...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreland, Blythe S., Oman, Kenji M., Bundschuh, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700779/
https://www.ncbi.nlm.nih.gov/pubmed/31426747
http://dx.doi.org/10.1186/s12859-019-3011-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700779/
https://www.ncbi.nlm.nih.gov/pubmed/31426747
http://dx.doi.org/10.1186/s12859-019-3011-2

Ejemplares similares