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Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

BACKGROUND: African Americans (AAs) experience premature chronic health outcomes and longevity disparities consistent with an accelerated aging phenotype. DNA methylation (DNAm) levels at specific CpG positions are hallmarks of aging evidenced by the presence of age-associated differentially methyla...

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Detalles Bibliográficos
Autores principales: Tajuddin, Salman M., Hernandez, Dena G., Chen, Brian H., Noren Hooten, Nicole, Mode, Nicolle A., Nalls, Mike A., Singleton, Andrew B., Ejiogu, Ngozi, Chitrala, Kumaraswamy Naidu, Zonderman, Alan B., Evans, Michele K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700815/
https://www.ncbi.nlm.nih.gov/pubmed/31426852
http://dx.doi.org/10.1186/s13148-019-0722-1